Gluconeogenesis Process - A Question and Brief Explanation

Gluconeogenesis - Question and Answer

In this video I have explained answer to one of my question on gluconeogenesis. I have also explained in brief about conversion of propionyl CoA to glucose while explaining the answer for this question.

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Gluconeogenesis - precursors and regulation

In this video I have explained how non-carbohydrate sources like lactate, alanine, propionyl CoA and glycerol are converted to glucose in gluconeogenesis process. All the important gluconeogenesis enzymes are explained with their function. Important enzymes fr each of the gluconeogenic precursors conversion into glucose is explained.

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Energy Sources During Fasting and Starvation

Biochemical Changes in Chronic Alcoholism

Answer to a Question on Uncoupler of Electron Transport Chain

In this video I have explained a question on uncouplers of electron transport chain. Chemical uncouplers are 2,4-Dinitrophenol, dinitrocresol, pentachlorophenaol. Physiological uncouplers are thermogenin, uncoupling proteins UCP1, UCP2, UCP3, UCP4, UCP5. All are present in various tissues like brown adipose tissue, skeletal muscle, brain, neurons, other tissues. Uncouplers increase BMR, body temperature, metabolic rate, increased rate of electron transport, increased O2 consumption, increased respiratory rate.

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Key words:
electron transport chain
uncouplers
2,4-dinitrophenol
thermogenin
T3 and T4
pentachlorophenol
temperature
basal metabolic rate
ATP synthesis
ATP synthase
redox potential
NADH
FADH2
complex I
complex II
cytochrome oxidase
ubiquionone
brown adipose tissue
BAT
UCP
O consumption
NAD
FAD
USMLE
step-1
Kaplan
biochemistry
Review video
Mungli

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Pyruvate Dehydrogenase Complex and Other Similar Enzyme Complexes.

In this video I have explained pyruvate dehydrogenase enzyme complex along with other two enzyme complexes that is alpha-ketoglutarate dehydrogenase complex and branched chain alpha-ketoacid dehydrogenase complex. I have specially emphasized on the E1, E2, and E3 subunits.

Thanks to my student Natalia Adorno Carvajal for meticulously recording this video.

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Key words:
pyruvate dehydrogenase complex
alpha-ketoglutarate dehydrogenase complex
branched chain alpha-ketoacid dehydrogenase complex
lipoate
pantothenate
thiamine pyrophosphate
NAD
FAD
Pyruvate
alpha-ketoglutarate
alpha ketoacid
USMLE
step-1
Kaplan
biochemistry
Review video
Mungli

Answer to a Question on Pentose Phosphate Pathway

In this video I have briefly explained a diseases related to pentose phosphate pathway (which is also referred as hexose monophosphate shunt). This disease in question is glucose 6-phosphate dehydrogenase deficiency (G6PD deficiency) which causes hemolytic anemia due to deficiency of NADPH. NADPH deficiency leads to decreased GSH (reduced glutathione) which leads to increased presence of reactive oxygen species (ROS). 

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Key words:
Glucose 6-phosphate
G6PD deficiency
species
ribose 5 phosphate
NADPH
GSH
glutathione
GSSG
ROS
Heinz bodies
hemolytic anemia
Beutler florescence
bite cells
quick review
Mungli
UMHS
antimalarial
sulfonamides
napthalene
hemolytic crisis
fava beans
favism
USMLE
step-1
Kaplan
biochemistry
Review video
Mungli

Pentose Phosphate Pathway - A Quick Review

In this video Im brief in explaining pentose phosphate pathway which is also referred as hexose monophosphate shunt. both oxidative and non oxidative phases are explained in brief. importance of both the phases are explained. Different cell scenarios are considered to explain the pathway.

Many thanks to my student Luis Andres Acosta for recording this video for me.

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Key words:
Glucose 6-phosphate
G6PD deficiency
species
ribose 5 phosphate
NADPH
GSH
glutathione
USMLE
step-1
Kaplan
biochemistry
Review video
Mungli
pentose
phosphate pathway
ribose 5 phosphate
nucleotide
detoxification
oxidative phase
transketolase
transaldolase
purine
pyrimidine
PRPP

Lipoprotein Abnormality - Dyslipidemia - A Quick Review

In this video I have briefly explained all lipoprotein abnormalities according to Freiderickson's classification of lipoprotein abnromality or dyslipidemia. Different types of lipoprotein abnormalitis (dyslipedemias) are explained using the case stem based question, the format of it is like USMLE step-1 style.
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Key words:
Lipase
lipoprotein
hepatic lipase
LDL
VLDL
IDL
Chylomicron
lipoprotein
chylomicronemia
hypertriglycerademia
hypercholesterolemia
LDL receptor
atherosclerosis
familial
lipoprotein
deficiency
combined
hyperlipidemia
dysbetalipoproteinemia
LCAT
CETP
HDL
Apo B
Apo A1
Apo CII
endothelium
usmle
step-1
Dr Mungli
Lipoprotein
metabolism

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