Bohr shift is basically an explanation for the transport of O2 from alveoli of lungs to peripheral tissues and transport of CO2 in the form of bicarbonate (H+ and HCO3) from peripheral tissue to the alveoli of lungs.
In lungs under high partial pressure of O2, Hb in RBC loads O2 and becomes oxygenated, when RBCs reach peripheral tissues where the partial pressure of O2 is less and CO2 is more and hence O2 is released.
The mechanism how the O2 is loaded onto Hb in lungs and how O2 is released in peripheral tissues in the presence of high CO2 is explained in my YouTube video below. Take a look at it to understand the mechanism. If you have any questions or comments, drop it in the comments section below.
http://www.youtube.com/watch?v=Yf321BoP2jA
In lungs under high partial pressure of O2, Hb in RBC loads O2 and becomes oxygenated, when RBCs reach peripheral tissues where the partial pressure of O2 is less and CO2 is more and hence O2 is released.
The mechanism how the O2 is loaded onto Hb in lungs and how O2 is released in peripheral tissues in the presence of high CO2 is explained in my YouTube video below. Take a look at it to understand the mechanism. If you have any questions or comments, drop it in the comments section below.
http://www.youtube.com/watch?v=Yf321BoP2jA
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