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I'm a physician doctor with an MD degree. My passion for teaching has always been appreciated by students with whom I have shared my knowledge. I'm a passionate teacher of medical biochemistry and would like to share my knowledge about this beautiful subject with all those who is interested to learn to understand the cellular metabolic events and to understand the metabolic disease process. I would like to learn new things by keeping myself updated with current research in the field. Let us share the knowledge each other!!

Saturday, March 18, 2017

Brown Adipose Tissue



In this video I have explained briefly about three types of adipose tissues: white adipose tissue, brown adipose tissue and biege adipose tissue. The brown adipose tissue is abundantly seen in neonates and the quantity of it decreases as neonate develops into infant, child, adolescent and adult.
Brown adipose tissue has more mitochondria with high expression of an uncoupler protein called thermogenin. Thermogenin is also referred as uncouplin protein 1 (UCP1). Thermogenin acts as uncoupler of electron transport chain and uncouple oxidation from phosphorylation in electron transport chain. This way thermogenin in brown adipose tissue decreases the efficiency of electron transport chain thereby decreasing effective ATP generation from substrate oxidation.

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