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St. Kitts & Nevis
I'm a physician doctor with an MD degree. My passion for teaching has always been appreciated by students with whom I have shared my knowledge. I'm a passionate teacher of medical biochemistry and would like to share my knowledge about this beautiful subject with all those who is interested to learn to understand the cellular metabolic events and to understand the metabolic disease process. I would like to learn new things by keeping myself updated with current research in the field. Let us share the knowledge each other!!
Showing posts with label pyruvate. Show all posts
Showing posts with label pyruvate. Show all posts

Saturday, March 18, 2017

ATPs from Glucose Oxidation



In this video I have explained net ATPs coming from oxidation of glucose. While explaining the glycolysis process, I have explained  net ATPs coming from oxidation of glucose to 2 pyruvate under aerobic condition. ATPs coming from glycolysis under anaerobic condition, anaerobic glycolysis and ATPs coming from complete oxidation of glucose into 6 CO2 in the TCA cycle. I have also covered difference in the ATP yield both using malate aspartate shuttle and glycerol phosphate shuttle. 

Wednesday, October 12, 2016

Pyruvate Dehydrogenase Complex - Regulation



In this video I have explained all the points related to regulation of pyruvate dehydrogenase enzyme complex. Pyruvate dehydrogenase enzyme complex is also written as PDH complex or simple PDC. It has feedback regulation, allosteric modulation, covalent modification mediated by insulin and glucagon. In fasting condition its activity will decrease and in fed condition its activity will increase. NADH, acetyl CoA have a negative effect on PDH, ADP and pyruvate and Ca2+ will have a positive effect on PDH complex.

Why Lactose is an End Product of Anaerobic Glycolysis?



In this video I have explained the reason for why lactate is the end product of glycolysis under anaerobic situation or in cell which do not have mitochondria like red blood cells (RBCs). I have also briefly explained glycolysis that is oxidation of glucose to pyruvate and the energy yield from oxidation of glucose to pyruvate.