Proteoglycans and Glycosaminoglycans

In this video I have explained all that you need to know in proteoglycans and glycosaminoglycans. All in brief and high yield points.

Hurler Syndrome, Hunter Syndrome and Sanfilippo Syndrome

In this video I have explained all the high yield and most important things that you need to remember for Hurler syndrome, hunter syndrome and Sanfilippo syndrome. All the things you will need while you prepare for USMLE step1 for these three disorders.

Integration of Glucose and Galactose Metabolism

This video is about how glucose metabolism is linked to galactose metabolism. Glucose oxidation  product glucose 1-phosphate is converted to  UDP-glucose which is need ed for galactose metabolism. I have explained important enzymes involved in the conversion pathway. I have highlighted the applied aspects in the video. Importance of UDP-glucose in variety of reactions has been explained.

Brown Adipose Tissue

In this video I have explained briefly about three types of adipose tissues: white adipose tissue, brown adipose tissue and biege adipose tissue. The brown adipose tissue is abundantly seen in neonates and the quantity of it decreases as neonate develops into infant, child, adolescent and adult.
Brown adipose tissue has more mitochondria with high expression of an uncoupler protein called thermogenin. Thermogenin is also referred as uncouplin protein 1 (UCP1). Thermogenin acts as uncoupler of electron transport chain and uncouple oxidation from phosphorylation in electron transport chain. This way thermogenin in brown adipose tissue decreases the efficiency of electron transport chain thereby decreasing effective ATP generation from substrate oxidation.

ATPs from Glucose Oxidation

In this video I have explained net ATPs coming from oxidation of glucose. While explaining the glycolysis process, I have explained  net ATPs coming from oxidation of glucose to 2 pyruvate under aerobic condition. ATPs coming from glycolysis under anaerobic condition, anaerobic glycolysis and ATPs coming from complete oxidation of glucose into 6 CO2 in the TCA cycle. I have also covered difference in the ATP yield both using malate aspartate shuttle and glycerol phosphate shuttle.