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I'm a physician doctor with an MD degree. My passion for teaching has always been appreciated by students with whom I have shared my knowledge. I'm a passionate teacher of medical biochemistry and would like to share my knowledge about this beautiful subject with all those who is interested to learn to understand the cellular metabolic events and to understand the metabolic disease process. I would like to learn new things by keeping myself updated with current research in the field. Let us share the knowledge each other!!

Wednesday, September 10, 2014

Question on Protein structural organization

Which part of the protein is generally resistant for degradation, why is it so and name some diseases where this type of protein fragment being accumulated in various tissues? 

2 comments:

Jenna Ulrich said...

B-sheets because they are mostly hydrophobic and resist degradation. This can be seen in diseases such as alzheimer disease, prion disease and amyloidosis.

Dorcas Lomo said...

Beta pleated sheets because of it's hydrophobic amino acids. Alzheimer and creutzfeldt-jakob